Drug interactions
Bleomycin + Meningococcal group b vaccine
Severity: Moderate
Bleomycin and Meningococcal group b vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chemotherapy may blunt antibody responses to the non-live vaccine, leaving the patient less protected than expected.
What this interaction means in plain words
Bleomycin and Meningococcal group b vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cytotoxic therapy suppresses lymphocyte function and antibody production.
What to do
Vaccinate before chemotherapy when feasible, or after immune recovery. If given during treatment, consider revaccination later.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bleomycin
- Adenovirus types 4 and 7 live + Bleomycin Contraindicated
- Bleomycin + Brentuximab Contraindicated
- Bleomycin + Brentuximab vedotin Contraindicated
- Bleomycin + Dengue vaccine Major
- Bleomycin + Trastuzumab deruxtecan Major
- Bleomycin + Cholera vaccine Moderate
Frequently asked questions
Can I take Bleomycin with Meningococcal group b vaccine?
MediHelp rates the interaction as moderate. Bleomycin and Meningococcal group b vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chemotherapy may blunt antibody responses to the non-live vaccine, leaving the patient less protected than expected.
How serious is the interaction between Bleomycin and Meningococcal group b vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before chemotherapy when feasible, or after immune recovery. If given during treatment, consider revaccination later.
What other medicines interact with Bleomycin?
MediHelp also lists interactions of Bleomycin with, for example, Adenovirus types 4 and 7 live, Brentuximab, Brentuximab vedotin. The full list is on the Bleomycin page.
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