Drug interactions
Brimonidine + Flibanserin
Severity: Minor
Brimonidine and Flibanserin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brimonidine can cause drowsiness and some systemic hypotension, particularly if absorbed systemically, and flibanserin causes sedation and hypotension. Additive effects are possible but are likely small with ophthalmic use.
What this interaction means in plain words
Brimonidine and Flibanserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brimonidine belongs to Miscellaneous; Flibanserin belongs to Genitourinary.
Why it happens
Additive CNS depression and hypotension from alpha-2 agonism and flibanserin.
What to do
Counsel the patient about additive drowsiness. Monitor for dizziness and excessive sedation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Brimonidine
- Brimonidine + Isocarboxazid Contraindicated
- Brimonidine + Linezolid Contraindicated
- Brimonidine + Phenelzine Contraindicated
- Brimonidine + Procarbazine Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Brimonidine + Selegiline Contraindicated
Frequently asked questions
Can I take Brimonidine with Flibanserin?
MediHelp rates the interaction as minor. Brimonidine and Flibanserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brimonidine can cause drowsiness and some systemic hypotension, particularly if absorbed systemically, and flibanserin causes sedation and hypotension. Additive effects are possible but are likely small with ophthalmic use.
How serious is the interaction between Brimonidine and Flibanserin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about additive drowsiness. Monitor for dizziness and excessive sedation.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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