Drug interactions
Brimonidine + Haloperidol
Severity: Minor
Brimonidine and Haloperidol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brimonidine is an alpha-2 agonist that can cause drowsiness and hypotension, mainly after systemic absorption. With haloperidol it may add to sedation. With ophthalmic use the systemic exposure is small.
What this interaction means in plain words
Brimonidine and Haloperidol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brimonidine belongs to Miscellaneous; Haloperidol belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Counsel the patient about drowsiness and monitor sedation if both are used. No dose change is usually needed with ophthalmic brimonidine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Brimonidine
- Brimonidine + Isocarboxazid Contraindicated
- Brimonidine + Linezolid Contraindicated
- Brimonidine + Phenelzine Contraindicated
- Brimonidine + Procarbazine Contraindicated
- Brimonidine + Rasagiline Contraindicated
- Brimonidine + Selegiline Contraindicated
Frequently asked questions
Can I take Brimonidine with Haloperidol?
MediHelp rates the interaction as minor. Brimonidine and Haloperidol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brimonidine is an alpha-2 agonist that can cause drowsiness and hypotension, mainly after systemic absorption. With haloperidol it may add to sedation. With ophthalmic use the systemic exposure is small.
How serious is the interaction between Brimonidine and Haloperidol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about drowsiness and monitor sedation if both are used. No dose change is usually needed with ophthalmic brimonidine.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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