Drug interactions
Brivaracetam + Mirtazapine
Severity: Moderate
Brivaracetam and Mirtazapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents commonly cause somnolence and dizziness, so combined use can increase drowsiness and impair coordination and alertness. This is typically manageable but relevant in older adults and those who drive.
What this interaction means in plain words
Brivaracetam and Mirtazapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brivaracetam belongs to Central Nervous System; Mirtazapine belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects of two centrally acting drugs.
What to do
Monitor for sedation, dizziness and falls, especially during dose titration. Consider giving mirtazapine at bedtime.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mirtazapine
- Isocarboxazid + Mirtazapine Contraindicated
- Mirtazapine + Phenelzine Contraindicated
- Mirtazapine + Pimozide Contraindicated
- Mirtazapine + Procarbazine Contraindicated
- Mirtazapine + Rasagiline Contraindicated
- Mirtazapine + Selegiline Contraindicated
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Mirtazapine?
MediHelp rates the interaction as moderate. Brivaracetam and Mirtazapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents commonly cause somnolence and dizziness, so combined use can increase drowsiness and impair coordination and alertness. This is typically manageable but relevant in older adults and those who drive.
How serious is the interaction between Brivaracetam and Mirtazapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation, dizziness and falls, especially during dose titration. Consider giving mirtazapine at bedtime.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.
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