Drug interactions
Bromfenac + Latanoprost
Severity: Minor
Bromfenac and Latanoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Topical NSAIDs given with prostaglandin analogues have been linked to variable effects on intraocular pressure, and both agents can cause ocular inflammation or macular edema changes. Bromfenac may blunt the pressure-lowering effect of latanoprost in some patients, but findings are inconsistent.
What this interaction means in plain words
Bromfenac and Latanoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bromfenac belongs to Musculoskeletal; Latanoprost belongs to Miscellaneous.
Why it happens
Possible pharmacodynamic interference of NSAID cyclooxygenase inhibition with prostaglandin analogue activity; the mechanism is not established.
What to do
Check intraocular pressure when bromfenac is started or stopped, and adjust glaucoma therapy if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Latanoprost
- Bimatoprost + Latanoprost Moderate
- Latanoprost + Latanoprostene bunod Moderate
- Latanoprost + Tafluprost Moderate
- Latanoprost + Travoprost Moderate
- Aspirin rectal + Latanoprost Minor
- Aspirin + Latanoprost Minor
Other interactions of Bromfenac
- Bimatoprost + Bromfenac Minor
Frequently asked questions
Can I take Bromfenac with Latanoprost?
MediHelp rates the interaction as minor. Bromfenac and Latanoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Topical NSAIDs given with prostaglandin analogues have been linked to variable effects on intraocular pressure, and both agents can cause ocular inflammation or macular edema changes. Bromfenac may blunt the pressure-lowering effect of latanoprost in some patients, but findings are inconsistent.
How serious is the interaction between Bromfenac and Latanoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check intraocular pressure when bromfenac is started or stopped, and adjust glaucoma therapy if control changes.
What other medicines interact with Latanoprost?
MediHelp also lists interactions of Latanoprost with, for example, Bimatoprost, Latanoprostene bunod, Tafluprost. The full list is on the Latanoprost page.
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