Drug interactions
Brompheniramine + Ziprasidone
Severity: Minor
Brompheniramine and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating antihistamine and may increase drowsiness and psychomotor impairment when taken with ziprasidone. It also adds anticholinergic effects, which may matter in older adults.
What this interaction means in plain words
Brompheniramine and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brompheniramine belongs to Respiratory; Ziprasidone belongs to Central Nervous System.
Why it happens
Additive central nervous system depression and anticholinergic effects.
What to do
Warn the patient about sedation and avoid driving until the response is known. Consider a non-sedating antihistamine if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Ziprasidone?
MediHelp rates the interaction as minor. Brompheniramine and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Brompheniramine is a sedating antihistamine and may increase drowsiness and psychomotor impairment when taken with ziprasidone. It also adds anticholinergic effects, which may matter in older adults.
How serious is the interaction between Brompheniramine and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn the patient about sedation and avoid driving until the response is known. Consider a non-sedating antihistamine if needed.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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