Drug interactions
Budesonide-formoterol + Levofloxacin
Severity: Moderate
Budesonide-formoterol and Levofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levofloxacin can prolong the QT interval, and formoterol may add to this effect. The combination raises the risk of torsades de pointes in susceptible patients, particularly with hypokalemia.
What this interaction means in plain words
Budesonide-formoterol and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Levofloxacin belongs to Anti Bacterial.
Why it happens
Additive effects on cardiac repolarization, with beta2-agonist hypokalemia increasing risk.
What to do
Monitor ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Choose a non-fluoroquinolone antibiotic if the patient has several risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide-formoterol and Levofloxacin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide-formoterol
Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Frequently asked questions
Can I take Budesonide-formoterol with Levofloxacin?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levofloxacin can prolong the QT interval, and formoterol may add to this effect. The combination raises the risk of torsades de pointes in susceptible patients, particularly with hypokalemia.
How serious is the interaction between Budesonide-formoterol and Levofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Choose a non-fluoroquinolone antibiotic if the patient has several risk factors.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
