Drug interactions
Budesonide-formoterol + Primaquine
Severity: Moderate
Budesonide-formoterol and Primaquine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Primaquine has been associated with QT prolongation, and formoterol may contribute additively along with hypokalemia. The clinical risk is usually modest but is relevant in patients with other QT risk factors.
What this interaction means in plain words
Budesonide-formoterol and Primaquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Primaquine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Check ECG and electrolytes in patients with cardiac disease or other QT-prolonging drugs. Monitor for palpitations or syncope during primaquine courses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Primaquine
- Pimozide + Primaquine Contraindicated
- Amiodarone + Primaquine Major
- Amisulpride + Primaquine Major
- Anagrelide + Primaquine Major
- Arsenic trioxide + Primaquine Major
- Asenapine + Primaquine Major
Frequently asked questions
Can I take Budesonide-formoterol with Primaquine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Primaquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Primaquine has been associated with QT prolongation, and formoterol may contribute additively along with hypokalemia. The clinical risk is usually modest but is relevant in patients with other QT risk factors.
How serious is the interaction between Budesonide-formoterol and Primaquine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes in patients with cardiac disease or other QT-prolonging drugs. Monitor for palpitations or syncope during primaquine courses.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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