Drug interactions
Budesonide-formoterol + Procarbazine
Severity: Moderate
Budesonide-formoterol and Procarbazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Procarbazine has weak monoamine oxidase inhibitor activity. MAOIs may potentiate the cardiovascular effects of beta-2 agonists such as formoterol, leading to palpitations, tachycardia or blood pressure changes.
What this interaction means in plain words
Budesonide-formoterol and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Procarbazine belongs to Oncology.
Why it happens
Weak MAO inhibition by procarbazine may enhance adrenergic cardiovascular effects of formoterol.
What to do
Monitor heart rate, blood pressure and ECG if symptoms occur. Consider an alternative bronchodilator if cardiovascular effects emerge.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Budesonide-formoterol with Procarbazine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Procarbazine has weak monoamine oxidase inhibitor activity. MAOIs may potentiate the cardiovascular effects of beta-2 agonists such as formoterol, leading to palpitations, tachycardia or blood pressure changes.
How serious is the interaction between Budesonide-formoterol and Procarbazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG if symptoms occur. Consider an alternative bronchodilator if cardiovascular effects emerge.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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