Drug interactions
Cabozantinib + Cidofovir
Severity: Minor
Cabozantinib and Cidofovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cabozantinib is a substrate of MRP2, and cidofovir has been suggested to affect this transporter. The clinical relevance is uncertain and not well established.
What this interaction means in plain words
Cabozantinib and Cidofovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cabozantinib belongs to Oncology; Cidofovir belongs to Anti Virals.
Why it happens
Theoretical MRP2 inhibition raising cabozantinib exposure; not established for cidofovir.
What to do
Monitor for cabozantinib adverse effects such as diarrhea, hypertension and hand-foot syndrome, and reduce dose per labeling if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cabozantinib and Cidofovir, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Cidofovir
- Amikacin + Cidofovir Contraindicated
- Amphotericin b deoxycholate + Cidofovir Contraindicated
- Amphotericin b + Cidofovir Contraindicated
- Bacitracin + Cidofovir Contraindicated
- Capreomycin + Cidofovir Contraindicated
- Cephaloridine + Cidofovir Contraindicated
Other interactions of Cabozantinib
Frequently asked questions
Can I take Cabozantinib with Cidofovir?
MediHelp rates the interaction as minor. Cabozantinib and Cidofovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cabozantinib is a substrate of MRP2, and cidofovir has been suggested to affect this transporter. The clinical relevance is uncertain and not well established.
How serious is the interaction between Cabozantinib and Cidofovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for cabozantinib adverse effects such as diarrhea, hypertension and hand-foot syndrome, and reduce dose per labeling if they occur.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
