Drug interactions
Calcium + Chromium
Severity: Minor
Calcium and Chromium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium carbonate may reduce the absorption of oral chromium supplements. The clinical effect is likely small and rarely matters.
What this interaction means in plain words
Calcium and Chromium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium belongs to Gastrointestinal Tract; Chromium belongs to Gastrointestinal Tract.
Why it happens
Antacid-related rise in gastric pH and binding in the gut may reduce chromium absorption.
What to do
Separate doses by about 2 hours if both are taken.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Chromium
- Chromium + Omadacycline Moderate
- Chromium + Sarecycline Moderate
- Acarbose + Chromium Minor
- Acetylsalicylic acid + Chromium Minor
- Alogliptin-metformin + Chromium Minor
- Alogliptin-pioglitazone + Chromium Minor
Frequently asked questions
Can I take Calcium with Chromium?
MediHelp rates the interaction as minor. Calcium and Chromium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium carbonate may reduce the absorption of oral chromium supplements. The clinical effect is likely small and rarely matters.
How serious is the interaction between Calcium and Chromium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours if both are taken.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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