Drug interactions
Calcium + Gabapentin enacarbil
Severity: Minor
Calcium and Gabapentin enacarbil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids are known to reduce gabapentin bioavailability, and a similar effect is expected for gabapentin enacarbil's active drug. Reduced seizure or neuropathic pain control is possible.
What this interaction means in plain words
Calcium and Gabapentin enacarbil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium belongs to Gastrointestinal Tract; Gabapentin enacarbil belongs to Central Nervous System.
Why it happens
Reduced gastrointestinal absorption, likely via binding or altered pH.
What to do
Take gabapentin enacarbil at least 2 hours apart from calcium antacids and assess symptom control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Gabapentin enacarbil
Frequently asked questions
Can I take Calcium with Gabapentin enacarbil?
MediHelp rates the interaction as minor. Calcium and Gabapentin enacarbil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids are known to reduce gabapentin bioavailability, and a similar effect is expected for gabapentin enacarbil's active drug. Reduced seizure or neuropathic pain control is possible.
How serious is the interaction between Calcium and Gabapentin enacarbil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take gabapentin enacarbil at least 2 hours apart from calcium antacids and assess symptom control.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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