Drug interactions
Calcium + Nimodipine
Severity: Minor
Calcium and Nimodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
An increase in nimodipine exposure from higher gastric pH is not well supported, since nimodipine absorption is not meaningfully pH-dependent. Oral calcium has no important documented effect on nimodipine.
What this interaction means in plain words
Calcium and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium belongs to Gastrointestinal Tract; Nimodipine belongs to Cardiovascular.
Why it happens
No established mechanism; any effect via gastric pH is theoretical.
What to do
No specific action is required. Monitor blood pressure as usual during nimodipine therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Calcium with Nimodipine?
MediHelp rates the interaction as minor. Calcium and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. An increase in nimodipine exposure from higher gastric pH is not well supported, since nimodipine absorption is not meaningfully pH-dependent. Oral calcium has no important documented effect on nimodipine.
How serious is the interaction between Calcium and Nimodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required. Monitor blood pressure as usual during nimodipine therapy.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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