Drug interactions
Calcium carbonate + Deferiprone
Severity: Moderate
Calcium carbonate and Deferiprone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferiprone chelates polyvalent cations such as calcium in the gut. Taking it with calcium carbonate may reduce deferiprone absorption and weaken iron chelation.
What this interaction means in plain words
Calcium carbonate and Deferiprone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Deferiprone belongs to Miscellaneous.
Why it happens
Chelation of deferiprone by calcium ions in the gastrointestinal tract reduces its oral absorption.
What to do
Separate deferiprone from calcium carbonate by at least 4 hours. Monitor serum ferritin to confirm chelation efficacy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Calcium carbonate and Deferiprone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Calcium carbonate
Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Calcium carbonate with Deferiprone?
MediHelp rates the interaction as moderate. Calcium carbonate and Deferiprone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferiprone chelates polyvalent cations such as calcium in the gut. Taking it with calcium carbonate may reduce deferiprone absorption and weaken iron chelation.
How serious is the interaction between Calcium carbonate and Deferiprone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate deferiprone from calcium carbonate by at least 4 hours. Monitor serum ferritin to confirm chelation efficacy.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
