Drug interactions
Calcium carbonate + Fosinopril
Severity: Minor
Calcium carbonate and Fosinopril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids containing calcium may slightly reduce absorption of some ACE inhibitors, with fosinopril most often cited. The clinical effect on blood pressure is usually small.
What this interaction means in plain words
Calcium carbonate and Fosinopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Fosinopril belongs to Cardiovascular.
Why it happens
Possible reduced gastrointestinal absorption of fosinopril when given with antacids; the mechanism is not firmly established.
What to do
Separate doses by about 2 hours and monitor blood pressure if antacids are taken regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Fosinopril
- Aliskiren + Fosinopril Contraindicated
- Fosinopril + Protein a column Contraindicated
- Fosinopril + Sacubitril / valsartan Contraindicated
- Fosinopril + Sacubitril-valsartan Contraindicated
- Amifostine + Fosinopril Major
- Amiloride + Fosinopril Major
Frequently asked questions
Can I take Calcium carbonate with Fosinopril?
MediHelp rates the interaction as minor. Calcium carbonate and Fosinopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids containing calcium may slightly reduce absorption of some ACE inhibitors, with fosinopril most often cited. The clinical effect on blood pressure is usually small.
How serious is the interaction between Calcium carbonate and Fosinopril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours and monitor blood pressure if antacids are taken regularly.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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