Drug interactions
Calcium carbonate + Gliclazide
Severity: Minor
Calcium carbonate and Gliclazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium carbonate antacid raises gastric pH and could theoretically modify gliclazide absorption. No meaningful clinical effect on glucose control is established.
What this interaction means in plain words
Calcium carbonate and Gliclazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Gliclazide belongs to Endocrine.
Why it happens
Altered gastric pH may slightly change sulfonylurea dissolution and absorption; the effect is theoretical.
What to do
No routine action is needed; consider spacing doses by a couple of hours. Check glucose if antacid use is frequent.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Other interactions of Calcium carbonate
Frequently asked questions
Can I take Calcium carbonate with Gliclazide?
MediHelp rates the interaction as minor. Calcium carbonate and Gliclazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium carbonate antacid raises gastric pH and could theoretically modify gliclazide absorption. No meaningful clinical effect on glucose control is established.
How serious is the interaction between Calcium carbonate and Gliclazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; consider spacing doses by a couple of hours. Check glucose if antacid use is frequent.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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