Drug interactions
Calcium carbonate + Lisinopril
Severity: Minor
Calcium carbonate and Lisinopril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium antacids may slightly reduce ACE inhibitor absorption, but lisinopril is not known to be significantly affected. Clinical relevance is minimal.
What this interaction means in plain words
Calcium carbonate and Lisinopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Lisinopril belongs to Cardiovascular.
Why it happens
Possible small reduction in gastrointestinal absorption; the mechanism is not established.
What to do
No routine action; separate doses by 2 hours if blood pressure control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Other interactions of Lisinopril
- Aliskiren + Lisinopril Contraindicated
- Lisinopril + Protein a column Contraindicated
- Lisinopril + Sacubitril / valsartan Contraindicated
- Lisinopril + Sacubitril-valsartan Contraindicated
- Amifostine + Lisinopril Major
- Amiloride + Lisinopril Major
Frequently asked questions
Can I take Calcium carbonate with Lisinopril?
MediHelp rates the interaction as minor. Calcium carbonate and Lisinopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium antacids may slightly reduce ACE inhibitor absorption, but lisinopril is not known to be significantly affected. Clinical relevance is minimal.
How serious is the interaction between Calcium carbonate and Lisinopril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; separate doses by 2 hours if blood pressure control worsens.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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