Drug interactions
Calcium carbonate + Strontium ranelate
Severity: Moderate
Calcium carbonate and Strontium ranelate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium reduces strontium ranelate absorption when taken together, lowering its exposure and potentially efficacy.
What this interaction means in plain words
Calcium carbonate and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Strontium ranelate belongs to Musculoskeletal.
Why it happens
Strontium forms complexes with calcium in the gut and competes for absorption.
What to do
Take strontium ranelate at least 2 hours apart from calcium, for example at bedtime at least 2 hours after food and calcium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium carbonate
Other interactions of Strontium ranelate
Frequently asked questions
Can I take Calcium carbonate with Strontium ranelate?
MediHelp rates the interaction as moderate. Calcium carbonate and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium reduces strontium ranelate absorption when taken together, lowering its exposure and potentially efficacy.
How serious is the interaction between Calcium carbonate and Strontium ranelate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take strontium ranelate at least 2 hours apart from calcium, for example at bedtime at least 2 hours after food and calcium.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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