Drug interactions
Calcium chloride + Vitamin d
Severity: Moderate
Calcium chloride and Vitamin d: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vitamin D increases calcium absorption, and with calcium chloride, the additional calcium load can cause hypercalcemia in susceptible patients. Intravenous calcium chloride is typically used acutely, so risk is greatest with repeated use.
What this interaction means in plain words
Calcium chloride and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Vitamin D promotes calcium absorption and mobilization, adding to administered calcium.
What to do
Monitor serum calcium and adjust doses of either agent if levels rise.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vitamin d
Frequently asked questions
Can I take Calcium chloride with Vitamin d?
MediHelp rates the interaction as moderate. Calcium chloride and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases calcium absorption, and with calcium chloride, the additional calcium load can cause hypercalcemia in susceptible patients. Intravenous calcium chloride is typically used acutely, so risk is greatest with repeated use.
How serious is the interaction between Calcium chloride and Vitamin d?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and adjust doses of either agent if levels rise.
What other medicines interact with Vitamin d?
MediHelp also lists interactions of Vitamin d with, for example, Aluminum hydroxide, Amlodipine-hydrochlorothiazide-valsartan, Amlodipine-olmesartan-hydrochlorothiazide. The full list is on the Vitamin d page.
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