Drug interactions
Calcium gluconate + Vitamin a
Severity: Minor
Calcium gluconate and Vitamin a: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High doses of vitamin A may contribute to hypercalcemia, and combining with calcium supplementation could add to the risk. The effect mainly matters with large chronic vitamin A doses.
What this interaction means in plain words
Calcium gluconate and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium gluconate belongs to Gastrointestinal Tract; Vitamin a belongs to Gastrointestinal Tract.
Why it happens
Excess vitamin A increases bone resorption, adding to calcium load.
What to do
Monitor serum calcium if high-dose vitamin A and intravenous calcium are used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicated
- Calcium gluconate + Digoxin Major
- Alendronate + Calcium gluconate Moderate
- Amlodipine-atorvastatin + Calcium gluconate Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderate
Other interactions of Vitamin a
- Acitretin + Vitamin a Major
- Etretinate + Vitamin a Major
- Isotretinoin + Vitamin a Major
- Palovarotene + Vitamin a Major
- Bexarotene + Vitamin a Moderate
- Minocycline + Vitamin a Moderate
Frequently asked questions
Can I take Calcium gluconate with Vitamin a?
MediHelp rates the interaction as minor. Calcium gluconate and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High doses of vitamin A may contribute to hypercalcemia, and combining with calcium supplementation could add to the risk. The effect mainly matters with large chronic vitamin A doses.
How serious is the interaction between Calcium gluconate and Vitamin a?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium if high-dose vitamin A and intravenous calcium are used together.
What other medicines interact with Calcium gluconate?
MediHelp also lists interactions of Calcium gluconate with, for example, Ceftriaxone, Digoxin, Alendronate. The full list is on the Calcium gluconate page.
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