Drug interactions
Canagliflozin-metformin + Desogestrel
Severity: Minor
Canagliflozin-metformin and Desogestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hormonal contraceptives containing progestins can slightly worsen glucose tolerance and may reduce the effect of antidiabetic drugs. In most patients the effect is small and clinically manageable.
What this interaction means in plain words
Canagliflozin-metformin and Desogestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Canagliflozin-metformin belongs to Endocrine; Desogestrel belongs to Endocrine.
Why it happens
Progestins can reduce insulin sensitivity, producing a pharmacodynamic opposition to glucose-lowering drugs.
What to do
Monitor blood glucose when starting or stopping the contraceptive and adjust antidiabetic therapy if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Canagliflozin-metformin and Desogestrel, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Canagliflozin-metformin
Other interactions of Desogestrel
- Carbamazepine + Desogestrel Major
- Berotralstat + Desogestrel Moderate
- Desogestrel + Lamotrigine Moderate
- Desogestrel + Mifepristone Moderate
- Desogestrel + Warfarin Moderate
- Alogliptin-metformin + Desogestrel Minor
Frequently asked questions
Can I take Canagliflozin-metformin with Desogestrel?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Desogestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hormonal contraceptives containing progestins can slightly worsen glucose tolerance and may reduce the effect of antidiabetic drugs. In most patients the effect is small and clinically manageable.
How serious is the interaction between Canagliflozin-metformin and Desogestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping the contraceptive and adjust antidiabetic therapy if control changes.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
