Drug interactions
Canagliflozin-metformin + Fluvoxamine
Severity: Minor
Canagliflozin-metformin and Fluvoxamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
SSRIs such as fluvoxamine may alter glycemic control, with occasional hypoglycemia reported alongside antidiabetic drugs. The effect is generally small.
What this interaction means in plain words
Canagliflozin-metformin and Fluvoxamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Canagliflozin-metformin belongs to Endocrine; Fluvoxamine belongs to Central Nervous System.
Why it happens
Mechanism is not well established; possible effects on insulin sensitivity.
What to do
Monitor blood glucose when starting or stopping fluvoxamine and adjust antidiabetic doses if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Canagliflozin-metformin
Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Frequently asked questions
Can I take Canagliflozin-metformin with Fluvoxamine?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Fluvoxamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. SSRIs such as fluvoxamine may alter glycemic control, with occasional hypoglycemia reported alongside antidiabetic drugs. The effect is generally small.
How serious is the interaction between Canagliflozin-metformin and Fluvoxamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping fluvoxamine and adjust antidiabetic doses if needed.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
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