Drug interactions
Canagliflozin-metformin + Phentermine
Severity: Minor
Canagliflozin-metformin and Phentermine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine is a sympathomimetic that may modestly raise blood glucose, but its weight loss effect usually improves glycemia. Net changes in glucose control are variable and typically small.
What this interaction means in plain words
Canagliflozin-metformin and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Canagliflozin-metformin belongs to Endocrine; Phentermine belongs to Central Nervous System.
Why it happens
Sympathomimetic effects may raise glucose, offset by weight-loss-related improvement in insulin sensitivity.
What to do
Monitor blood glucose when phentermine is started or stopped and adjust antidiabetic therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Canagliflozin-metformin
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Canagliflozin-metformin with Phentermine?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phentermine is a sympathomimetic that may modestly raise blood glucose, but its weight loss effect usually improves glycemia. Net changes in glucose control are variable and typically small.
How serious is the interaction between Canagliflozin-metformin and Phentermine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when phentermine is started or stopped and adjust antidiabetic therapy if needed.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
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