Drug interactions
Candesartan + Insulin glargine
Severity: Minor
Candesartan and Insulin glargine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may enhance insulin sensitivity and so increase the glucose-lowering effect of insulin. Hypoglycemia is occasionally reported, mostly early in combined therapy.
What this interaction means in plain words
Candesartan and Insulin glargine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Candesartan belongs to Cardiovascular; Insulin glargine belongs to Endocrine.
Why it happens
ARBs may improve insulin sensitivity and peripheral glucose uptake, adding to insulin effect.
What to do
Monitor blood glucose when starting or stopping candesartan and reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Candesartan
- Aliskiren + Candesartan Contraindicated
- Candesartan + Sparsentan Contraindicated
- Amifostine + Candesartan Major
- Amiloride + Candesartan Major
- Amlodipine-benazepril + Candesartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Candesartan Major
Other interactions of Insulin glargine
Frequently asked questions
Can I take Candesartan with Insulin glargine?
MediHelp rates the interaction as minor. Candesartan and Insulin glargine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may enhance insulin sensitivity and so increase the glucose-lowering effect of insulin. Hypoglycemia is occasionally reported, mostly early in combined therapy.
How serious is the interaction between Candesartan and Insulin glargine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping candesartan and reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Candesartan?
MediHelp also lists interactions of Candesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Candesartan page.
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