Drug interactions
Candesartan-hydrochlorothiazide + Cefprozil
Severity: Minor
Candesartan-hydrochlorothiazide and Cefprozil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides may reduce the renal tubular secretion of cefprozil, slightly raising its levels. This is rarely clinically important at usual doses.
What this interaction means in plain words
Candesartan-hydrochlorothiazide and Cefprozil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Candesartan-hydrochlorothiazide belongs to Cardiovascular; Cefprozil belongs to Anti Bacterial.
Why it happens
Possible competition for anionic renal tubular secretion.
What to do
No routine action is needed. Consider the effect only in patients with severe renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Candesartan-hydrochlorothiazide
- Aliskiren + Candesartan-hydrochlorothiazide Contraindicated
- Candesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Candesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Candesartan-hydrochlorothiazide Major
- Amifostine + Candesartan-hydrochlorothiazide Major
- Amiloride + Candesartan-hydrochlorothiazide Major
Other interactions of Cefprozil
- Amikacin + Cefprozil Moderate
- Bcg vaccine live + Cefprozil Moderate
- Cefprozil + Cholera vaccine Moderate
- Cefprozil + Gentamicin Moderate
- Cefprozil + Microbiota Moderate
- Cefprozil + Plazomicin Moderate
Frequently asked questions
Can I take Candesartan-hydrochlorothiazide with Cefprozil?
MediHelp rates the interaction as minor. Candesartan-hydrochlorothiazide and Cefprozil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides may reduce the renal tubular secretion of cefprozil, slightly raising its levels. This is rarely clinically important at usual doses.
How serious is the interaction between Candesartan-hydrochlorothiazide and Cefprozil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Consider the effect only in patients with severe renal impairment.
What other medicines interact with Candesartan-hydrochlorothiazide?
MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.
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