Drug interactions
Captopril + Iron sucrose
Severity: Minor
Captopril and Iron sucrose: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intravenous iron sucrose can occasionally cause transient hypotension during or shortly after infusion. Concurrent ACE inhibitor therapy may make blood pressure drops more noticeable, though the clinical effect is generally small.
What this interaction means in plain words
Captopril and Iron sucrose have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Captopril belongs to Cardiovascular; Iron sucrose belongs to Miscellaneous.
Why it happens
Infusion-related vasodilatory hypotension from iron may add to ACE inhibitor blood pressure lowering; mechanism not firmly established.
What to do
Monitor blood pressure during and after the infusion and slow the rate if hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril
- Aliskiren + Captopril Contraindicated
- Captopril + Sacubitril / valsartan Contraindicated
- Captopril + Sacubitril-valsartan Contraindicated
- Amifostine + Captopril Major
- Amiloride + Captopril Major
- Amlodipine-hydrochlorothiazide-valsartan + Captopril Major
Other interactions of Iron sucrose
- Dextrose 5% + Iron sucrose Contraindicated
- Deferasirox + Iron sucrose Moderate
- Deferiprone + Iron sucrose Moderate
- Deferoxamine + Iron sucrose Moderate
- Amlodipine-benazepril + Iron sucrose Minor
- Benazepril + Iron sucrose Minor
Frequently asked questions
Can I take Captopril with Iron sucrose?
MediHelp rates the interaction as minor. Captopril and Iron sucrose have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intravenous iron sucrose can occasionally cause transient hypotension during or shortly after infusion. Concurrent ACE inhibitor therapy may make blood pressure drops more noticeable, though the clinical effect is generally small.
How serious is the interaction between Captopril and Iron sucrose?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during and after the infusion and slow the rate if hypotension develops.
What other medicines interact with Captopril?
MediHelp also lists interactions of Captopril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Captopril page.
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