Drug interactions
Deferoxamine + Iron sucrose
Severity: Moderate
Deferoxamine and Iron sucrose: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron sucrose is given intravenously, so gut absorption is not the issue, but deferoxamine binds iron and promotes its elimination, opposing iron repletion.
What this interaction means in plain words
Deferoxamine and Iron sucrose can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferoxamine belongs to Miscellaneous; Iron sucrose belongs to Miscellaneous.
Why it happens
Deferoxamine chelates iron and promotes its excretion, counteracting iron repletion.
What to do
Avoid combining unless deficiency is clearly documented. Monitor ferritin and transferrin saturation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Iron sucrose
- Dextrose 5% + Iron sucrose Contraindicated
- Deferasirox + Iron sucrose Moderate
- Deferiprone + Iron sucrose Moderate
- Amlodipine-benazepril + Iron sucrose Minor
- Benazepril + Iron sucrose Minor
- Captopril-hydrochlorothiazide + Iron sucrose Minor
Other interactions of Deferoxamine
Frequently asked questions
Can I take Deferoxamine with Iron sucrose?
MediHelp rates the interaction as moderate. Deferoxamine and Iron sucrose can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron sucrose is given intravenously, so gut absorption is not the issue, but deferoxamine binds iron and promotes its elimination, opposing iron repletion.
How serious is the interaction between Deferoxamine and Iron sucrose?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining unless deficiency is clearly documented. Monitor ferritin and transferrin saturation.
What other medicines interact with Iron sucrose?
MediHelp also lists interactions of Iron sucrose with, for example, Dextrose 5%, Deferasirox, Deferiprone. The full list is on the Iron sucrose page.
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