Drug interactions
Carbachol + Cyclizine
Severity: Minor
Carbachol and Cyclizine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbachol is a muscarinic and nicotinic agonist, whereas cyclizine blocks muscarinic receptors, so cyclizine may reduce carbachol's effects. Significance is limited because carbachol is mainly used locally in the eye.
What this interaction means in plain words
Carbachol and Cyclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbachol belongs to Miscellaneous; Cyclizine belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism at muscarinic receptors.
What to do
Monitor for reduced miotic or cholinergic response and adjust therapy if the effect is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclizine
- Calcium / magnesium / potassium / sodium oxybates + Cyclizine Major
- Cyclizine + Henbane Major
- Cyclizine + Sodium oxybate Major
- Abobotulinumtoxina + Cyclizine Moderate
- Alfentanil + Cyclizine Moderate
- Alprazolam + Cyclizine Moderate
Other interactions of Carbachol
- Atropine + Carbachol Moderate
- Bethanechol + Carbachol Moderate
- Carbachol + Darifenacin Moderate
- Carbachol + Dicyclomine Moderate
- Carbachol + Donepezil Moderate
- Carbachol + Flavoxate Moderate
Frequently asked questions
Can I take Carbachol with Cyclizine?
MediHelp rates the interaction as minor. Carbachol and Cyclizine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carbachol is a muscarinic and nicotinic agonist, whereas cyclizine blocks muscarinic receptors, so cyclizine may reduce carbachol's effects. Significance is limited because carbachol is mainly used locally in the eye.
How serious is the interaction between Carbachol and Cyclizine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced miotic or cholinergic response and adjust therapy if the effect is inadequate.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.
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