Drug interactions
Carbinoxamine + Cariprazine
Severity: Moderate
Carbinoxamine and Cariprazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbinoxamine is a sedating first-generation antihistamine, and it can add to cariprazine-induced drowsiness and slowed psychomotor performance. Additive anticholinergic effects may also occur.
What this interaction means in plain words
Carbinoxamine and Cariprazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbinoxamine belongs to Respiratory; Cariprazine belongs to Central Nervous System.
Why it happens
Additive CNS depression from H1-receptor antagonism and antipsychotic receptor blockade.
What to do
Counsel about additive drowsiness and avoid driving until response is known. Consider a non-sedating antihistamine as an alternative.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cariprazine
Other interactions of Carbinoxamine
- Alprazolam + Carbinoxamine Moderate
- Amisulpride + Carbinoxamine Moderate
- Amitriptyline + Carbinoxamine Moderate
- Amobarbital + Carbinoxamine Moderate
- Asenapine + Carbinoxamine Moderate
- Azelastine-fluticasone + Carbinoxamine Moderate
Frequently asked questions
Can I take Carbinoxamine with Cariprazine?
MediHelp rates the interaction as moderate. Carbinoxamine and Cariprazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbinoxamine is a sedating first-generation antihistamine, and it can add to cariprazine-induced drowsiness and slowed psychomotor performance. Additive anticholinergic effects may also occur.
How serious is the interaction between Carbinoxamine and Cariprazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel about additive drowsiness and avoid driving until response is known. Consider a non-sedating antihistamine as an alternative.
What other medicines interact with Cariprazine?
MediHelp also lists interactions of Cariprazine with, for example, Alfentanil, Amisulpride, Amobarbital. The full list is on the Cariprazine page.
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