Drug interactions
Delafloxacin + Ferrous gluconate
Severity: Moderate
Delafloxacin and Ferrous gluconate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron chelates oral delafloxacin and can markedly reduce its absorption. This may cause subtherapeutic antibiotic levels and treatment failure.
What this interaction means in plain words
Delafloxacin and Ferrous gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Ferrous gluconate belongs to Miscellaneous.
Why it happens
Iron cations chelate the fluoroquinolone in the gastrointestinal tract, decreasing absorption.
What to do
Give oral delafloxacin at least 2 hours before or 6 hours after iron.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous gluconate
Other interactions of Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderate
- Calcium carbonate + Delafloxacin Moderate
- Calcium + Delafloxacin Moderate
- Carbonyl iron + Delafloxacin Moderate
- Delafloxacin + Didanosine Moderate
- Delafloxacin + Ferrous fumarate Moderate
Frequently asked questions
Can I take Delafloxacin with Ferrous gluconate?
MediHelp rates the interaction as moderate. Delafloxacin and Ferrous gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron chelates oral delafloxacin and can markedly reduce its absorption. This may cause subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Delafloxacin and Ferrous gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after iron.
What other medicines interact with Ferrous gluconate?
MediHelp also lists interactions of Ferrous gluconate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous gluconate page.
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