Skip to content

Drug interactions

Cariprazine + Methocarbamol

Severity: Minor

Cariprazine and Methocarbamol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cariprazine can cause somnolence and akathisia, and methocarbamol adds CNS depressant effects. Together they may increase drowsiness and impair alertness and coordination.

What this interaction means in plain words

Cariprazine and Methocarbamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cariprazine belongs to Central Nervous System; Methocarbamol belongs to Musculoskeletal.

Evidence level: Low

Why it happens

Additive CNS depressant effects.

What to do

Counsel the patient about drowsiness and driving. Reduce the dose of one drug if sedation is troublesome.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Cariprazine and Methocarbamol, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Cariprazine with Methocarbamol?

MediHelp rates the interaction as minor. Cariprazine and Methocarbamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cariprazine can cause somnolence and akathisia, and methocarbamol adds CNS depressant effects. Together they may increase drowsiness and impair alertness and coordination.

How serious is the interaction between Cariprazine and Methocarbamol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about drowsiness and driving. Reduce the dose of one drug if sedation is troublesome.

What other medicines interact with Methocarbamol?

MediHelp also lists interactions of Methocarbamol with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Methocarbamol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in