Drug interactions
Carisoprodol + Rucaparib
Severity: Minor
Carisoprodol and Rucaparib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rucaparib inhibits CYP2C19, which converts carisoprodol to meprobamate, so carisoprodol levels may rise. This could modestly increase sedation and dizziness.
What this interaction means in plain words
Carisoprodol and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carisoprodol belongs to Musculoskeletal; Rucaparib belongs to Oncology.
Why it happens
Rucaparib inhibits CYP2C19-mediated metabolism of carisoprodol.
What to do
Monitor for excessive sedation and reduce the carisoprodol dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carisoprodol
Other interactions of Rucaparib
- Cisapride + Rucaparib Major
- Ergotamine + Rucaparib Major
- Pimozide + Rucaparib Major
- Alfuzosin + Rucaparib Moderate
- Aripiprazole + Rucaparib Moderate
- Atorvastatin + Rucaparib Moderate
Frequently asked questions
Can I take Carisoprodol with Rucaparib?
MediHelp rates the interaction as minor. Carisoprodol and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rucaparib inhibits CYP2C19, which converts carisoprodol to meprobamate, so carisoprodol levels may rise. This could modestly increase sedation and dizziness.
How serious is the interaction between Carisoprodol and Rucaparib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and reduce the carisoprodol dose if needed.
What other medicines interact with Carisoprodol?
MediHelp also lists interactions of Carisoprodol with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Carisoprodol page.
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