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Drug interactions

Carmustine + Digoxin

Severity: Minor

Carmustine and Digoxin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cytotoxic chemotherapy can damage the intestinal mucosa and impair absorption of oral digoxin tablets, lowering levels. Specific data for carmustine are limited.

What this interaction means in plain words

Carmustine and Digoxin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Carmustine belongs to Oncology; Digoxin belongs to Cardiovascular.

Evidence level: Low

Why it happens

Chemotherapy-related mucosal injury may reduce gastrointestinal absorption of digoxin.

What to do

Monitor clinical response and digoxin levels during chemotherapy and adjust dose if needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Carmustine with Digoxin?

MediHelp rates the interaction as minor. Carmustine and Digoxin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cytotoxic chemotherapy can damage the intestinal mucosa and impair absorption of oral digoxin tablets, lowering levels. Specific data for carmustine are limited.

How serious is the interaction between Carmustine and Digoxin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response and digoxin levels during chemotherapy and adjust dose if needed.

What other medicines interact with Digoxin?

MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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