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Drug interactions

Cat's claw + Infliximab

Severity: Minor

Cat's claw and Infliximab: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cat's claw has reported immunomodulatory activity, and its effect in patients on infliximab is not well defined. It may either oppose or alter the therapeutic effect of TNF inhibition.

What this interaction means in plain words

Cat's claw and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Cat's claw may modulate immune function and TNF-alpha production, but the mechanism and clinical significance are not established.

What to do

Advise patients to avoid cat's claw while on infliximab. Monitor disease activity if the supplement is used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cat's claw with Infliximab?

MediHelp rates the interaction as minor. Cat's claw and Infliximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cat's claw has reported immunomodulatory activity, and its effect in patients on infliximab is not well defined. It may either oppose or alter the therapeutic effect of TNF inhibition.

How serious is the interaction between Cat's claw and Infliximab?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid cat's claw while on infliximab. Monitor disease activity if the supplement is used.

What other medicines interact with Infliximab?

MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.

Full monographs, dosing and an interaction checker in the MediHelp app

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