Drug interactions
Cefadroxil + Furosemide
Severity: Minor
Cefadroxil and Furosemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Some cephalosporins have been associated with additive kidney injury when given with potent loop diuretics, especially in volume-depleted or older patients. Cefadroxil is a first-generation oral cephalosporin with little nephrotoxicity of its own, so the risk is modest. Furosemide may also reduce renal clearance of cefadroxil if dehydration occurs.
What this interaction means in plain words
Cefadroxil and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefadroxil belongs to Anti Bacterial; Furosemide belongs to Cardiovascular.
Why it happens
Diuretic-induced volume depletion and reduced renal perfusion may add to cephalosporin renal effects and slow its elimination.
What to do
Maintain hydration and monitor serum creatinine in patients with renal impairment or volume depletion. Adjust cefadroxil dose to renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Cefadroxil with Furosemide?
MediHelp rates the interaction as minor. Cefadroxil and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Some cephalosporins have been associated with additive kidney injury when given with potent loop diuretics, especially in volume-depleted or older patients. Cefadroxil is a first-generation oral cephalosporin with little nephrotoxicity of its own, so the risk is modest. Furosemide may also reduce renal clearance of cefadroxil if dehydration occurs.
How serious is the interaction between Cefadroxil and Furosemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Maintain hydration and monitor serum creatinine in patients with renal impairment or volume depletion. Adjust cefadroxil dose to renal function.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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