Drug interactions
Cefdinir + Ibuprofen
Severity: Minor
Cefdinir and Ibuprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are acidic compounds eliminated partly by renal tubular secretion, so a small rise in ibuprofen levels is theoretically possible. No clinically meaningful effect has been established.
What this interaction means in plain words
Cefdinir and Ibuprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefdinir belongs to Anti Bacterial; Ibuprofen belongs to Musculoskeletal.
Why it happens
Theoretical competition for renal tubular anionic secretion.
What to do
No dose change is needed. Routine awareness only.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Other interactions of Cefdinir
- Aluminum hydroxide + Cefdinir Moderate
- Cefdinir + Cholera vaccine Moderate
- Cefdinir + Famotidine Moderate
- Cefdinir + Gentamicin Moderate
- Cefdinir + Microbiota Moderate
- Cefdinir + Nizatidine Moderate
Frequently asked questions
Can I take Cefdinir with Ibuprofen?
MediHelp rates the interaction as minor. Cefdinir and Ibuprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are acidic compounds eliminated partly by renal tubular secretion, so a small rise in ibuprofen levels is theoretically possible. No clinically meaningful effect has been established.
How serious is the interaction between Cefdinir and Ibuprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Routine awareness only.
What other medicines interact with Ibuprofen?
MediHelp also lists interactions of Ibuprofen with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Ibuprofen page.
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