Drug interactions
Cefotetan + Chlorpropamide
Severity: Minor
Cefotetan and Chlorpropamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefotetan is an organic acid that may compete with chlorpropamide for renal tubular secretion. Any rise in chlorpropamide exposure is probably small.
What this interaction means in plain words
Cefotetan and Chlorpropamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefotetan belongs to Anti Bacterial; Chlorpropamide belongs to Endocrine.
Why it happens
Competition for renal tubular anionic secretion.
What to do
No routine adjustment is needed. Monitor glucose during therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlorpropamide
Other interactions of Cefotetan
- Cefotetan + Dronabinol Contraindicated
- Cefotetan + Warfarin Major
- Amikacin + Cefotetan Moderate
- Argatroban + Cefotetan Moderate
- Cefotetan + Dalteparin Moderate
- Cefotetan + Enoxaparin Moderate
Frequently asked questions
Can I take Cefotetan with Chlorpropamide?
MediHelp rates the interaction as minor. Cefotetan and Chlorpropamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefotetan is an organic acid that may compete with chlorpropamide for renal tubular secretion. Any rise in chlorpropamide exposure is probably small.
How serious is the interaction between Cefotetan and Chlorpropamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor glucose during therapy.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
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