Drug interactions
Celecoxib + Emtricitabine
Severity: Minor
Celecoxib and Emtricitabine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Emtricitabine is eliminated by the kidney through filtration and tubular secretion, and NSAIDs can impair renal function. Together they may raise exposure to renally cleared drugs, with a modest risk of kidney-related toxicity.
What this interaction means in plain words
Celecoxib and Emtricitabine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Emtricitabine belongs to Anti Virals.
Why it happens
NSAID-related reduction in renal perfusion and possible competition for tubular secretion decrease emtricitabine clearance.
What to do
Monitor renal function with prolonged or high-dose NSAID use. Adjust emtricitabine dosing if creatinine clearance declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Emtricitabine
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Emtricitabine Contraindicated
- Atidarsagene autotemcel + Emtricitabine Major
- Betibeglogene autotemcel + Emtricitabine Major
- Elivaldogene autotemcel + Emtricitabine Major
- Emtricitabine + Lamivudine Major
- Emtricitabine + Lovotibeglogene autotemcel Major
Frequently asked questions
Can I take Celecoxib with Emtricitabine?
MediHelp rates the interaction as minor. Celecoxib and Emtricitabine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Emtricitabine is eliminated by the kidney through filtration and tubular secretion, and NSAIDs can impair renal function. Together they may raise exposure to renally cleared drugs, with a modest risk of kidney-related toxicity.
How serious is the interaction between Celecoxib and Emtricitabine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function with prolonged or high-dose NSAID use. Adjust emtricitabine dosing if creatinine clearance declines.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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