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Drug interactions

Ceritinib + Formoterol

Severity: Moderate

Ceritinib and Formoterol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both drugs can prolong the QT interval. Used together they may add to the risk of torsades de pointes, particularly in patients with hypokalemia, bradycardia, or structural heart disease.

What this interaction means in plain words

Ceritinib and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ceritinib belongs to Oncology; Formoterol belongs to Respiratory.

Evidence level: Moderate

Why it happens

Additive QTc prolongation through pharmacodynamic effects on cardiac repolarization.

What to do

Obtain an ECG and check electrolytes (potassium, magnesium) before and during combined use. Correct electrolyte abnormalities and reassess therapy if QTc becomes markedly prolonged.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ceritinib with Formoterol?

MediHelp rates the interaction as moderate. Ceritinib and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval. Used together they may add to the risk of torsades de pointes, particularly in patients with hypokalemia, bradycardia, or structural heart disease.

How serious is the interaction between Ceritinib and Formoterol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and check electrolytes (potassium, magnesium) before and during combined use. Correct electrolyte abnormalities and reassess therapy if QTc becomes markedly prolonged.

What other medicines interact with Formoterol?

MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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