Drug interactions
Chloramphenicol + Paricalcitol
Severity: Minor
Chloramphenicol and Paricalcitol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloramphenicol may increase paricalcitol exposure, raising the possibility of hypercalcemia.
What this interaction means in plain words
Chloramphenicol and Paricalcitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chloramphenicol belongs to Anti Bacterial; Paricalcitol belongs to Musculoskeletal.
Why it happens
CYP3A4 inhibition may reduce paricalcitol metabolism.
What to do
Monitor serum calcium and phosphorus during combined use, and reduce the paricalcitol dose if hypercalcemia appears.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Chloramphenicol and Paricalcitol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Chloramphenicol
Other interactions of Paricalcitol
- Carbamazepine + Paricalcitol Moderate
- Cholestyramine + Paricalcitol Moderate
- Clarithromycin + Paricalcitol Moderate
- Digoxin + Paricalcitol Moderate
- Ketoconazole + Paricalcitol Moderate
- Paricalcitol + Posaconazole Moderate
Frequently asked questions
Can I take Chloramphenicol with Paricalcitol?
MediHelp rates the interaction as minor. Chloramphenicol and Paricalcitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloramphenicol may increase paricalcitol exposure, raising the possibility of hypercalcemia.
How serious is the interaction between Chloramphenicol and Paricalcitol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and phosphorus during combined use, and reduce the paricalcitol dose if hypercalcemia appears.
What other medicines interact with Chloramphenicol?
MediHelp also lists interactions of Chloramphenicol with, for example, Adagrasib, Avapritinib, Bcg vaccine live. The full list is on the Chloramphenicol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
