Drug interactions
Chlordiazepoxide-clidinium + Ramelteon
Severity: Minor
Chlordiazepoxide-clidinium and Ramelteon: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ramelteon is a melatonin receptor agonist with a mild sedative effect, and combined with a benzodiazepine it may modestly add to drowsiness. Significant potentiation has not been well demonstrated.
What this interaction means in plain words
Chlordiazepoxide-clidinium and Ramelteon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlordiazepoxide-clidinium belongs to Gastrointestinal Tract; Ramelteon belongs to Central Nervous System.
Why it happens
Mild additive sedation through different receptor systems.
What to do
Counsel patients about additive drowsiness and caution with driving. No dose change is generally needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlordiazepoxide-clidinium
- Alfentanil + Chlordiazepoxide-clidinium Major
- Alprazolam + Chlordiazepoxide-clidinium Major
- Amobarbital + Chlordiazepoxide-clidinium Major
- Belladonna and opium + Chlordiazepoxide-clidinium Major
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium Major
- Brexanolone + Chlordiazepoxide-clidinium Major
Other interactions of Ramelteon
- Calcium / magnesium / potassium / sodium oxybates + Ramelteon Contraindicated
- Fluvoxamine + Ramelteon Contraindicated
- Ramelteon + Sodium oxybate Contraindicated
- Alfentanil + Ramelteon Moderate
- Amitriptyline + Ramelteon Moderate
- Amobarbital + Ramelteon Moderate
Frequently asked questions
Can I take Chlordiazepoxide-clidinium with Ramelteon?
MediHelp rates the interaction as minor. Chlordiazepoxide-clidinium and Ramelteon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ramelteon is a melatonin receptor agonist with a mild sedative effect, and combined with a benzodiazepine it may modestly add to drowsiness. Significant potentiation has not been well demonstrated.
How serious is the interaction between Chlordiazepoxide-clidinium and Ramelteon?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about additive drowsiness and caution with driving. No dose change is generally needed.
What other medicines interact with Chlordiazepoxide-clidinium?
MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.
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