Drug interactions
Chloroquine + Formoterol
Severity: Moderate
Chloroquine and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine can prolong the QT interval and cause arrhythmias, and formoterol may add QTc effects, tachycardia and hypokalemia. The combination may increase the risk of torsades de pointes, especially in patients with cardiac disease or electrolyte disturbance.
What this interaction means in plain words
Chloroquine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chloroquine belongs to Anti Parasitic; Formoterol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta2-agonist-induced hypokalemia.
What to do
Obtain a baseline ECG, correct potassium and magnesium, and monitor for palpitations or syncope; avoid adding other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Formoterol?
MediHelp rates the interaction as moderate. Chloroquine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine can prolong the QT interval and cause arrhythmias, and formoterol may add QTc effects, tachycardia and hypokalemia. The combination may increase the risk of torsades de pointes, especially in patients with cardiac disease or electrolyte disturbance.
How serious is the interaction between Chloroquine and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG, correct potassium and magnesium, and monitor for palpitations or syncope; avoid adding other QT-prolonging drugs.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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