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Drug interactions

Chloroquine + Indacaterol inhaled

Severity: Moderate

Chloroquine and Indacaterol inhaled: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Chloroquine prolongs the QT interval and indacaterol, a long-acting beta-2 agonist, can also affect QT and cause hypokalemia and tachycardia. Together they may modestly increase the risk of arrhythmia, particularly in patients with cardiac disease or electrolyte disturbance.

What this interaction means in plain words

Chloroquine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive QT prolongation, with beta-agonist-induced hypokalemia potentially enhancing the risk.

What to do

Check baseline ECG and potassium in patients with cardiac risk factors and correct electrolyte abnormalities. Monitor for palpitations or syncope during co-treatment.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chloroquine with Indacaterol inhaled?

MediHelp rates the interaction as moderate. Chloroquine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine prolongs the QT interval and indacaterol, a long-acting beta-2 agonist, can also affect QT and cause hypokalemia and tachycardia. Together they may modestly increase the risk of arrhythmia, particularly in patients with cardiac disease or electrolyte disturbance.

How serious is the interaction between Chloroquine and Indacaterol inhaled?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and potassium in patients with cardiac risk factors and correct electrolyte abnormalities. Monitor for palpitations or syncope during co-treatment.

What other medicines interact with Chloroquine?

MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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