Drug interactions
Chloroquine + Influenza virus vaccine trivalent adjuvanted
Severity: Minor
Chloroquine and Influenza virus vaccine trivalent adjuvanted: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine has immunomodulatory effects, but there is no convincing evidence that it meaningfully blunts the antibody response to inactivated influenza vaccine. The interaction is largely theoretical and vaccination should not be withheld.
What this interaction means in plain words
Chloroquine and Influenza virus vaccine trivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible mild immunomodulatory effect of chloroquine on vaccine response; not firmly established.
What to do
Vaccinate on the usual schedule without changing chloroquine therapy. No additional monitoring is needed beyond routine care.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Influenza virus vaccine trivalent adjuvanted?
MediHelp rates the interaction as minor. Chloroquine and Influenza virus vaccine trivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloroquine has immunomodulatory effects, but there is no convincing evidence that it meaningfully blunts the antibody response to inactivated influenza vaccine. The interaction is largely theoretical and vaccination should not be withheld.
How serious is the interaction between Chloroquine and Influenza virus vaccine trivalent adjuvanted?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate on the usual schedule without changing chloroquine therapy. No additional monitoring is needed beyond routine care.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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