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Drug interactions

Chloroquine + Influenza virus vaccine trivalent recombinant

Severity: Minor

Chloroquine and Influenza virus vaccine trivalent recombinant: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Chloroquine has immunomodulatory effects, but a clinically significant reduction in response to inactivated or recombinant influenza vaccine has not been established. The effect on vaccine response is theoretical.

What this interaction means in plain words

Chloroquine and Influenza virus vaccine trivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible immunomodulation by chloroquine; not well established.

What to do

Vaccinate as scheduled; no change in dosing is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chloroquine with Influenza virus vaccine trivalent recombinant?

MediHelp rates the interaction as minor. Chloroquine and Influenza virus vaccine trivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloroquine has immunomodulatory effects, but a clinically significant reduction in response to inactivated or recombinant influenza vaccine has not been established. The effect on vaccine response is theoretical.

How serious is the interaction between Chloroquine and Influenza virus vaccine trivalent recombinant?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as scheduled; no change in dosing is needed.

What other medicines interact with Chloroquine?

MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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