Drug interactions
Chloroquine + Lorcaserin
Severity: Minor
Chloroquine and Lorcaserin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lorcaserin inhibits CYP2D6 and may modestly raise chloroquine exposure. Clinical significance is likely small.
What this interaction means in plain words
Chloroquine and Lorcaserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Lorcaserin inhibits CYP2D6, reducing a minor pathway of chloroquine metabolism.
What to do
No routine adjustment; monitor for chloroquine adverse effects. Note that lorcaserin has been withdrawn from many markets.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Lorcaserin?
MediHelp rates the interaction as minor. Chloroquine and Lorcaserin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lorcaserin inhibits CYP2D6 and may modestly raise chloroquine exposure. Clinical significance is likely small.
How serious is the interaction between Chloroquine and Lorcaserin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment; monitor for chloroquine adverse effects. Note that lorcaserin has been withdrawn from many markets.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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