Drug interactions
Chloroquine + Ofatumumab sc
Severity: Minor
Chloroquine and Ofatumumab sc: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ofatumumab depletes B cells and chloroquine has mild immunomodulatory effects, so additive immunosuppression is possible. The clinical significance at usual chloroquine doses is uncertain.
What this interaction means in plain words
Chloroquine and Ofatumumab sc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive immunomodulatory effects; not well established.
What to do
Monitor for signs of infection during co-therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Ofatumumab sc?
MediHelp rates the interaction as minor. Chloroquine and Ofatumumab sc have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ofatumumab depletes B cells and chloroquine has mild immunomodulatory effects, so additive immunosuppression is possible. The clinical significance at usual chloroquine doses is uncertain.
How serious is the interaction between Chloroquine and Ofatumumab sc?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection during co-therapy.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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