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Drug interactions

Chloroquine + Rabies vaccine chick embryo cell derived

Severity: Moderate

Chloroquine and Rabies vaccine chick embryo cell derived: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Chloroquine has been reported to reduce antibody response to rabies vaccine given intradermally. Protection could be lower, although the effect with intramuscular dosing is uncertain.

What this interaction means in plain words

Chloroquine and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Possible attenuation of the vaccine immune response; mechanism not firmly established.

What to do

Use the intramuscular route in patients taking chloroquine and ideally finish the series before starting it. Check rabies antibody titers if exposure risk continues.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chloroquine with Rabies vaccine chick embryo cell derived?

MediHelp rates the interaction as moderate. Chloroquine and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine has been reported to reduce antibody response to rabies vaccine given intradermally. Protection could be lower, although the effect with intramuscular dosing is uncertain.

How serious is the interaction between Chloroquine and Rabies vaccine chick embryo cell derived?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the intramuscular route in patients taking chloroquine and ideally finish the series before starting it. Check rabies antibody titers if exposure risk continues.

What other medicines interact with Chloroquine?

MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.

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