Drug interactions
Chloroquine + Rabies vaccine chick embryo cell derived
Severity: Moderate
Chloroquine and Rabies vaccine chick embryo cell derived: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine has been reported to reduce antibody response to rabies vaccine given intradermally. Protection could be lower, although the effect with intramuscular dosing is uncertain.
What this interaction means in plain words
Chloroquine and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible attenuation of the vaccine immune response; mechanism not firmly established.
What to do
Use the intramuscular route in patients taking chloroquine and ideally finish the series before starting it. Check rabies antibody titers if exposure risk continues.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Rabies vaccine chick embryo cell derived?
MediHelp rates the interaction as moderate. Chloroquine and Rabies vaccine chick embryo cell derived can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine has been reported to reduce antibody response to rabies vaccine given intradermally. Protection could be lower, although the effect with intramuscular dosing is uncertain.
How serious is the interaction between Chloroquine and Rabies vaccine chick embryo cell derived?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the intramuscular route in patients taking chloroquine and ideally finish the series before starting it. Check rabies antibody titers if exposure risk continues.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
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