Drug interactions
Chloroquine + Sipuleucel-t
Severity: Minor
Chloroquine and Sipuleucel-t: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Immunosuppressive drugs may impair the immune activation that sipuleucel-T depends on. Chloroquine is only weakly immunomodulatory and the interaction is theoretical.
What this interaction means in plain words
Chloroquine and Sipuleucel-t have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible immunomodulatory effects of chloroquine could blunt the cellular immune response; the mechanism is not established.
What to do
No specific action is required. Consider whether chloroquine can be deferred around leukapheresis and infusion.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Chloroquine and Sipuleucel-t, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Sipuleucel-t?
MediHelp rates the interaction as minor. Chloroquine and Sipuleucel-t have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Immunosuppressive drugs may impair the immune activation that sipuleucel-T depends on. Chloroquine is only weakly immunomodulatory and the interaction is theoretical.
How serious is the interaction between Chloroquine and Sipuleucel-t?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required. Consider whether chloroquine can be deferred around leukapheresis and infusion.
What other medicines interact with Chloroquine?
MediHelp also lists interactions of Chloroquine with, for example, Cisapride, Dofetilide, Dronedarone. The full list is on the Chloroquine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
