Drug interactions
Cholera vaccine + Everolimus
Severity: Moderate
Cholera vaccine and Everolimus: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Everolimus is immunosuppressive and may reduce the immune response to oral cholera vaccine. Protection for travellers may be inadequate.
What this interaction means in plain words
Cholera vaccine and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
mTOR inhibition impairs lymphocyte proliferation and vaccine response.
What to do
Vaccinate before starting everolimus when possible and advise on food and water precautions; consider revaccination after immune recovery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Cholera vaccine with Everolimus?
MediHelp rates the interaction as moderate. Cholera vaccine and Everolimus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Everolimus is immunosuppressive and may reduce the immune response to oral cholera vaccine. Protection for travellers may be inadequate.
How serious is the interaction between Cholera vaccine and Everolimus?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before starting everolimus when possible and advise on food and water precautions; consider revaccination after immune recovery.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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